Medicinal benefits and scientific justification of Commiphora mukul (Muqil): A review

نویسندگان

چکیده

Commiphora mukul (Muqil or Guggul), oleo-gum, has been in use for thousands of years as a medicine Unani and Ayurvedic medicinal systems. It was primarily used swellings, inflammation, piles, arthritis urinary disorders. Among its various types Muqil-I-Arzaq, gum, having reddish hue is considered to be the best form Muqil purposes. revealed inhibit nuclear factor-kb, regulator inflammatory response, act potent antagonist receptors androgens, mineralocorticoides, glucocorticoides. versatile herb with diverse benefits which demand scientific validation. A coherent review properties, benefits, traditional uses studies Muqil, along overall processes involved from collection consumption judiciously described this paper. The aim provide base multiple research works, validating different chronic ailments.
 keywords: mukul, Inflammation, Nuclear factor-KB,

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cultivation and Conservation of Guggulu (Commiphora mukul)

Guggulu (Commiphora mukul) is about 2-3.5 mt heighted plant of Burceraceae family. The plant grows wild in the arid, rocky tracts, also in low rainy and hot areas. The part used in medicinal preparation is resin, collected by tapping the barks. Guggulu deserves high values in Ayurvedic medicines. Guggulu is Rasayana, Vatakaphaghna, and used in various diseases. Due to high values and excessive ...

متن کامل

Hypocholesterolemic effect of Commiphora mukul resin (guggal).

Alcohollc extract of C. mulnd resin (guggal) and one pure steroid isolated from this extract, when administered orally at a dose of 25-50 mgjkg body weight, reduced the serum cholesterol level in normal and triton-induced byperUpemlc rats and cholesterol-fed byperlipemIc rabbits. Both guggal extract and the steroid showed only slight inhibition of cholesterol biosynthesIs 85 compared to p_chlor...

متن کامل

In Vitro Studies on Thyrogenic Effect of Commiphora Mukul (guggulu)

The results of this study has revealed a significant increase in I(131) uptake of cultivated thyroid gland in the media containing petroleum ether extract of Commiphora mukul. Besides, T(3) resin uptake, protein bound iodine as well as free thyroxine index in the media are also observed to be significantly (P 0.001) increased. When explants are cultivated in the media containing melatonin, ther...

متن کامل

Rhabdomyolysis caused by Commiphora mukul, a natural lipid-lowering agent.

OBJECTIVE To report a case of rhabdomyolysis caused by Commiphora mukul, a natural lipid-lowering agent. CASE SUMMARY A 55-year-old man was taking an extract of C. mukul 300 mg 3 times daily to lower his cholesterol level. He developed rhabdomyolysis with hemoglobinuria after 2 weeks of treatment. Laboratory tests showed creatine kinase 144600 IU/L (reference range 24-195), myoglobin >3000 ng...

متن کامل

z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo.

Our previous studies have shown that z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. We now report a novel response to z-guggulsterone involving the inhibition of angiogenesis in vitro and in vivo. The z-guggulsterone treatment inhibited capillary-like tube formation (in vitro neovascul...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Drug Delivery and Therapeutics

سال: 2021

ISSN: ['2250-1177']

DOI: https://doi.org/10.22270/jddt.v11i1-s.4550